For the scientific mind to soar limitless horizons, a conducive environment is a primary requisite. In recognizing this need, Shantha has designed and developed a truly world-class research facility equipped with the latest tools of research in modern biotechnology, providing the scientists with the necessary wherewithal to carry on their work
Shantha is equipped with state-of-the-art R&D facility, ideally designed for development of biologics, based on modern biotechnology. The facility has 50,000 sq.ft of laboratory area, divided in four independent laboratories.
Main Lab used for molecular biology, immunology, microbial fermentation, purification and characterization.
Class 10,000 area facility for animal cell culture, hybridoma technology, virus handling and upstream and downstream process development.
Bacterial vaccine lab.
Viral vaccine lab (with a separate cell culture and virus handling area)
The support facilities include a library, lecture hall, central monitoring system and other essential services like centralized vacuum, compressed air, cold rooms and circulating distilled water and other essentials for a modern industrial R&D laboratory.
INSTRUMENT FACILITIES Automatic computer controlled bio-reactors of various capacities from 1L to 100L for microbial and mammalian cell culture provided with state-of-the-art accessories for exhaust gas analysis, perfusion and online nutrient and metabolite analysis.
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Cross-flow filtration systems of various types such as membrane, hollow fibre and ceramic, for handling filtration process upto a volume of 1000L.
Continuous flow centrifuge for handling large-scale separation processes upto a volume of 500L.
Homogenisers including a bead-mill and a high-pressure homogeniser for pilot scale cell disruption.
Sophisticated computer controlled chromatography systems for laboratory and pilot scale protein purification along with axial and radial flow and expanded bed columns of various sizes.
• Pilot scale lyophilisers for asceptic freeze-drying.
• Dry heat and steam sterilising equipments.
• Online methanol sensor for monitoring Pichia based fermentations.
• Other analytical instruments include Fluorescence and phase-contrast microscopes with camera and video attachments, Scanning Densitometer, Gel Documentation System, UV-VIS Spectrophotometer, Spectroflourimeter, HPCL, GC, Liquid Scintillation Counter, Oligonucleotide Synthesiser, Thermocyclers and Tunable UV-VIS Plate Reader.